Modern Fluoroorganic Chemistry_ Synthesis, Reactivity, Applications -Peer Kirsch -( John Wiley & Sons)

Peer Kirsch在海德堡大学获得化学类学士学位,随后在马普协会药物研究所获得博士学位。在日本RIKEN 研究所完成博士后研究后,加入了默克位于德国Darmstadt的液晶部分并从事含氟液晶的相关研究,Peer Kirsch也是Darmstadt工业大学的W3教授。其编著的《Modern Fluoroorganic Chemistry_ Synthesis, Reactivity, Applications》一书可作为氟化学领域的经典教材使用。

In this handbook, Peer Kirsch clearly shows that this exciting field is no longer an exotic area of research. Aimed primarily at synthetic chemists wanting to gain a deeper understanding of the fascinating implications of including the highly unusual element fluorine in organic compounds, the main part of the book presents a wide range of synthetic methodologies and the experimental procedures selected undeniably show that this can be done with standard laboratory equipment. To round off, the author looks at fluorous chemistry and the applications of organofluorine compounds in liquid crystals, polymers and more besides.
This long-awaited book represents an indispensable source of high quality information for everyone working in the field.

内容简介:《Modern Fluoroorganic Chemistry_ Synthesis, Reactivity, Applications》是一本系统介绍有机氟化学的新专著,以较大的篇幅介绍了在有机化合物中引入氟原子或含氟取代基的新方法(包括直接氟化法、全氟烷基化反应及含氟合成子法等),对各种氟化试剂(“亲电的”和“亲核的”)特性和应用做了详尽的讨论,并列举了大量的实用例子帮助理解。书中对和当前化学的热点之一绿色化学相关的氟两相化学的原理和应用也做了深入的介绍。书的后半部分对含氟有机化合物在各领域的应用做了全面的介绍,特别是对其在材料和药物方面的应用及其相关的作用机制的讨论颇为深入。

图书链接https://onlinelibrary.wiley.com/doi/book/10.1002/352760393X

图书目录

Introduction

Why Organofluorine Chemistry

The Unique Properties of Organofluorine Compounds

Synthesis of complex organofluorine compounds

Introduction of Fluorine

Perfluoroalkylation

Special Fluorinated Groups

Syntheses with Fluorinated Building Blocks.

Fluorous chemistry

Fluorous Biphasic Catalysis

Fluorous Synthesis and Combinatorial Chemistry

Fluoropharmaceuticals

Why Fluorinated Pharmaceuticals?

Lipophilicity

Hydrogen bonding and Electrostatic Interactions

Orthogonal Reactivity and Suicide Inhibition

Liquid crystals for active matrix LCDs

Calamitic Liquid Crystals: A Short Introduction

Functioning of an Active Matrix LCD

Why Fluorinated Liquid Crystals?